One of the world’s most respected neurologists, Professor Sam Berkovic’s seminal research has revolutionised understanding and approaches to human epilepsy. Sam’s original and meticulous research over 25 years has transformed diagnosis, enabled accurate genetic counselling and significantly improved treatment for patients. Sam’s work established the connection between genetics and epilepsy, with major global efforts now focused on gene discovery and understanding how genetic abnormalities cause seizures. Recognised at the highest international level, Sam has published more than 400 peer-reviewed articles relating to epilepsy and genetics; these have been cited in scientific publications more than 25,000 times. He is admired for his careful mentorship of young specialists, his leadership in building the Comprehensive Epilepsy Program at Austin Health, his work chairing international committees and his skill as a teacher and communicator. Sam leads his field with wisdom, intellect and skill and his research has put Australia at the forefront of global research into epilepsy while improving the lives of people around the globe.